Despite the overall similarity of light-induced geneexpression responses between Ngb-null mice and wt, the presentstudy aimed to investigate whether there are systemicgenotype-related differences in the retina. Specifically, the aimwas to identify the genes that are differentially expressed whenthe effect of light is ignored. Samples with identical genotypes(n=15) were pooled and it was found that there were severaldifferentially expressed genes between the pools (). The three main differentialexpression estimates from the array study were confirmed by RT-qPCR().


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